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REM sleep behaviour disorder (RBD): Personal perspectives and research priorities.
- Source :
-
Journal of Sleep Research . May2024, p1. 16p. 3 Illustrations. - Publication Year :
- 2024
-
Abstract
- Summary The formal identification and naming of rapid eye movement (REM) sleep behaviour disorder (RBD) in 1985–1987 is described; the historical background of RBD from 1966 to 1985 is briefly discussed; and RBD milestones are presented. Current knowledge on RBD is identified with reference to recent comprehensive reviews, allowing for a focus on research priorities for RBD: factors and predictors of neurodegenerative phenoconversion from isolated RBD and patient enrolment in neuroprotective trials; isolated RBD clinical research cohorts; epidemiology of RBD; traumatic brain injury, post‐traumatic stress disorder, RBD and neurodegeneration; depression, RBD and synucleinopathy; evolution of prodromal RBD to neurodegeneration; gut microbiome dysbiosis and colonic synuclein histopathology in isolated RBD; other alpha‐synuclein research in isolated RBD; narcolepsy‐RBD; dreams and nightmares in RBD; phasic REM sleep in isolated RBD; RBD, periodic limb movements, periodic limb movement disorder pseudo‐RBD; other neurophysiology research in RBD; cardiac scintigraphy (123I‐MIBG) in isolated RBD; brain magnetic resonance imaging biomarkers in isolated RBD; microRNAs as biomarkers in isolated RBD; actigraphic, other automated digital monitoring and machine learning research in RBD; prognostic counselling and ethical considerations in isolated RBD; and REM sleep basic science research. RBD research is flourishing, and is strategically situated at an ever‐expanding crossroads of clinical (sleep) medicine, neurology, psychiatry and neuroscience. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09621105
- Database :
- Academic Search Index
- Journal :
- Journal of Sleep Research
- Publication Type :
- Academic Journal
- Accession number :
- 177390248
- Full Text :
- https://doi.org/10.1111/jsr.14228