Integrated modeling of protein and RNA.

This article discusses the importance of proteins and RNAs in biological pathways and cell function. It highlights the recent advancements in understanding protein and RNA structure and function through computational and experimental techniques. The article also explores the potential applications of this research in developing therapeutic strategies for diseases such as cancer and COVID-19. It focuses on innovative experimental and computational methods used to model proteins and RNAs, including cryo-EM mapping, cross-linking techniques, and molecular dynamics simulations. Additionally, the article discusses the development of AI computational methodologies for complex structure prediction and drug repositioning. The authors hope that these methods will provide valuable insights and advancements in protein and RNA research. [Extracted from the article]