Successful recovery of aplastic anemia following orthotopic liver transplantation for non-A-E acute liver failure.

Rajwal SR, Davison SM, Stringer MD, Kinsey SE, McClean P. Successful recovery of aplastic anemia following orthotopic liver transplantation for non-A-E acute liver failure. Pediatr Transplantation 2005: 9: 537–540. © 2005 Blackwell Munksgaard This report describes a teenager who developed aplastic anemia (AA) because of non-A-E acute liver failure (ALF) requiring orthotopic liver transplantation (OLT). His AA did not recover spontaneously and he required treatment with ATG 9 months post-OLT. Bone marrow recovery occurred 4 months after immunotherapy and coincided with further intensification of immunusuppression required to treat early chronic rejection of the liver graft. Three years post-OLT he remains well with good bone marrow and liver function. Intensification of immunosuppression can lead to successful resolution of AA associated with non-A-E ALF. [ABSTRACT FROM AUTHOR]