Nanodiamonds as Lutetium-177 Carriers for Nuclear Medicine.

Authors :: Kazakov, A. G.
Babenya, J. S.
Ekatova, T. Y.
Vinokurov, S. E.
Khvorostinin, E. Y.
Ushakov, I. A.
Zukau, V. V.
Stasyuk, E. S.
Nesterov, E. A.
Sadkin, V. L.
Rogov, A. S.
Myasoedov, B. F.
Source :: Radiochemistry. Apr2024, Vol. 66 Issue 2, p191-197. 7p.
Publication Year :: 2024
Abstract: The work investigated the sorption of no-carrier-added 177Lu isolated from neutron-irradiated 176Yb2O3, and carrier-added 177Lu obtained by irradiation of natLu2O3, by commercial and oxidized nanodiamonds (NDs) of various grades from aqueous solutions to identify among them a promising carrier for further research in the field of nuclear medicine. A promising sorbent was found: oxidized NDs of the STP grade (ox-STP); conditions for the fast sorption of lutetium with it in an amount equivalent to 1.2 GBq of no-carrier-added 177Lu were determined, which corresponds to the activity used in therapy. [ABSTRACT FROM AUTHOR]