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Longitudinal changes in adverse effects reporting in multiple dietary supplement classifications: The US military dietary supplement use study.
- Source :
-
Food & Chemical Toxicology . Jun2024, Vol. 188, pN.PAG-N.PAG. 1p. - Publication Year :
- 2024
-
Abstract
- Over 70% of United States military service members (SMs) regularly use dietary supplements (DSs) and about 18% have reported adverse effects (AEs) associated with use. This investigation examined longitudinal changes in AEs reporting among DS users. On two separate occasions 1.3 ± 0.2 years apart (mean ± standard deviation), 5778 SMs completed identical questionnaires on DS use and associated AEs. Among SMs reporting DS use ≥1 time/week, ≥1 AE was reported by 19% and 15% in the baseline and follow-up phases, respectively. The risk of reporting DS use at follow-up was similar among those reporting and not reporting AEs at baseline for most DS categories including prohormones, proteins/amino acids, individual vitamins and minerals, multivitamin/multiminerals, herbals, fish oils, joint health products, and other DSs. An exception was combination products where those reporting AEs at baseline had an increased risk of use at follow-up (risk ratio = 1.13, 95% confidence interval = 1.06–1.09). Those reporting AEs at baseline and continuing DS use in the follow-up were more likely to report AEs at follow-up compared to those not reporting baseline AEs. In conclusion, AEs reported at baseline did not deter many participants from using DSs in the follow-up period, and many SMs reporting AEs at baseline continued reporting them at follow-up. [Display omitted] • How does previous experience with adverse effects (AEs) from ingested dietary supplements (DSs) affect future DS use? • AEs reported at baseline did not deter participants from using most types of DS at a 1.3 year follow-up. • Experienced AEs could be minor, or symptoms those expected by participants to indicate DS was functioning effectively. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02786915
- Volume :
- 188
- Database :
- Academic Search Index
- Journal :
- Food & Chemical Toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 177198300
- Full Text :
- https://doi.org/10.1016/j.fct.2024.114635