MORPHOLOGICAL, CYTOLOGICAL, BIOCHEMICAL AND BACTERIOLOGICAL STUDY OF CEREBROSPINAL FLUID (CSF) IN CHILDREN'S MENINGITIS.

18 cases from 2021, 17 cases from 2022 and 15 cases from 2023 were analyzed, in total 50 children, boys and girls. The following were recorded: the child's age, sex, environment of origin, the main biochemical parameters (amount of glucose, proteins, chlorine, number of elements, cytobacteriological parameters (normal or pathological cytology, presence of pathogens-meningococcus, pneumococcus, diplococcus) such as and the macroscopic appearance of the cerebrospinal fluid (color, transparency, appearance). The working methods were the classic ones (macroscopic, microscopic examination, Pandy reaction, culture on agarose gel, smear). In Bacău County, the most frequent meningitis were the bacterial forms that predominated with a percentage of 72% in 2021, while the viral forms predominated in 2022 with a percentage of 65% and in the year 2023 with a percentage of 60%. Bacterial meningitis registered in the 3 years at the level of Bacău County have as pathogens: Koch's bacillus 43%, meningococcus 36%, streptococcus 14%, unspecified etiology 7%. In bacterial forms, regardless of etiology, changes in C.S.F. they are the same. C.S.F. is clear, opalescent or hemorrhagic. Cytology is dominated by polymorphonuclear leukocytesreaching 100%. The biochemical changes are: hyperproteinorachia, up to 0 and hypochloruria. In viral forms, although the etiology is viral, the C.S.F. changes, biochemistry and cytology are similar. Thus, C.S.F. is normal, clear, or slightly opalescent. Predominantly polymorphonuclear. [ABSTRACT FROM AUTHOR]