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Hydrogel dressings for diabetic foot ulcer: A systematic review and meta‐analysis.
- Source :
-
Diabetes, Obesity & Metabolism . Jun2024, Vol. 26 Issue 6, p2305-2317. 13p. - Publication Year :
- 2024
-
Abstract
- Aim: To investigate the differences in utility between conventional dressings and hydrogel dressings for the treatment of diabetic foot ulcer (DFU). Methods: The PubMed, Embase, Cochrane Library, CNKI, VIP and Wanfang databases were systematically searched up to 21 January 2023. Fixed/random‐effect models were used to calculate the odds ratios (ORs) and mean differences (MDs) with 95% confidence intervals (CIs) for the effect size analysis, with heterogeneity determined by I2 statistics. Subgroup analyses of different classes of hydrogel were also conducted. Results: A total of 15 randomized controlled trials with 872 patients were eligible for the present analysis. Compared with conventional dressings, hydrogel dressings significantly improved the healing rate (OR 4.09, 95% CI 2.83 to 5.91), shortened the healing time (MD −11.38, 95% CI −13.11 to −9.66), enhanced granulation formation (MD −3.60, 95% CI −4.21 to −3.00) and epithelial formation (MD −2.82, 95% CI −3.19 to −2.46), and reduced the incidence of bacterial infection (OR 0.10, 95% CI 0.05 to 0.18). Conclusion: The meta‐analysis showed that hydrogel dressings are more effective in treating DFU compared with conventional dressings. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14628902
- Volume :
- 26
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Diabetes, Obesity & Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 177114105
- Full Text :
- https://doi.org/10.1111/dom.15544