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Mitochondrial dysfunction in lipid processing and gastrointestinal disorders.
- Source :
-
Trends in Endocrinology & Metabolism . May2024, Vol. 35 Issue 5, p364-366. 3p. - Publication Year :
- 2024
-
Abstract
- Mitochondrial dysfunctions predominantly cause encephalomyopathies with muscle atrophy and neurodegeneration. However, their impact on other tissues, particularly the gastrointestinal tract, requires further investigation. In a recent report in Nature , Moschandrea et al. used mice deficient in the mitochondrial aminoacyl-tRNA synthetase DARS2 to investigate the role of enterocytic mitochondria in dietary lipid processing and transport. Their work sheds light on the development of gastrointestinal disorders as a result of mitochondrial dysfunction. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10432760
- Volume :
- 35
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Trends in Endocrinology & Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 177031658
- Full Text :
- https://doi.org/10.1016/j.tem.2024.02.009