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FEN1-assisted DNA logic amplifier circuit for fast and compact DNA computing.
- Source :
-
Chemical Communications . 4/30/2024, Vol. 60 Issue 34, p4593-4596. 4p. - Publication Year :
- 2024
-
Abstract
- This work developed DNA amplifier logic gates (AND-OR, OR-AND, FAN-IN, FAN-OUT, and 4-bit square-root circuits) using a flap endonuclease 1 (FEN1)-catalyzed signal amplification reaction, for the fastest and compact DNA computing. Moreover, the logic circuit can use input strands with concentrations of less than 1 nM, which is more than 100 times lower than the input concentration of other DNA logic circuits, providing a promising methodology for constructing fast and compact DNA computations. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LOGIC circuits
*DNA
*AMPLIFICATION reactions
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 60
- Issue :
- 34
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 176784987
- Full Text :
- https://doi.org/10.1039/d4cc00203b