Back to Search Start Over

Near-infrared spectroscopy and electroencephalography neurofeedback for binge-eating disorder: an exploratory randomized trial.

Authors :
Hilbert, Anja
Rösch, Sarah Alica
Petroff, David
Prettin, Christiane
Lührs, Michael
Ehlis, Ann-Christin
Schmidt, Ricarda
Source :
Psychological Medicine. Mar2024, Vol. 54 Issue 4, p675-686. 12p.
Publication Year :
2024

Abstract

Background: Binge-eating disorder (BED) co-occurs with neurobehavioral alterations in the processing of disorder-relevant content such as visual food stimuli. Whether neurofeedback (NF) directly targeting them is suited for treatment remains unclear. This study sought to determine feasibility and estimate effects of individualized, functional near-infrared spectroscopy-based real-time NF (rtfNIRS-NF) and high-beta electroencephalography-based NF (EEG-NF), assuming superiority over waitlist (WL). Methods: Single-center, assessor-blinded feasibility study with randomization to rtfNIRS-NF, EEG-NF, or WL and assessments at baseline (t 0), postassessment (t 1), and 6-month follow-up (t 2). NF comprised 12 60-min food-specific rtfNIRS-NF or EEG-NF sessions over 8 weeks. Primary outcome was the binge-eating frequency at t 1 assessed interview-based. Secondary outcomes included feasibility, eating disorder symptoms, mental and physical health, weight management-related behavior, executive functions, and brain activity at t 1 and t 2. Results: In 72 patients (intent-to-treat), the results showed feasibility of NF regarding recruitment, attrition, adherence, compliance, acceptance, and assessment completion. Binge eating improved at t 1 by −8.0 episodes, without superiority of NF v. WL (−0.8 episodes, 95% CI −2.4 to 4.0), but with improved estimates in NF at t 2 relative to t 1. NF was better than WL for food craving, anxiety symptoms, and body mass index, but overall effects were mostly small. Brain activity changes were near zero. Conclusions: The results show feasibility of food-specific rtfNIRS-NF and EEG-NF in BED, and no posttreatment differences v. WL, but possible continued improvement of binge eating. Confirmatory and mechanistic evidence is warranted in a double-blind randomized design with long-term follow-up, considering dose–response relationships and modes of delivery. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00332917
Volume :
54
Issue :
4
Database :
Academic Search Index
Journal :
Psychological Medicine
Publication Type :
Academic Journal
Accession number :
176758343
Full Text :
https://doi.org/10.1017/S0033291723002350