A novel framework for lung cancer classification using lightweight convolutional neural networks and ridge extreme learning machine model with SHapley Additive exPlanations (SHAP).

This paper presents a novel approach that merges a lightweight parallel depth-wise separable convolutional neural network (LPDCNN) with a ridge regression extreme learning machine (Ridge-ELM) for precise classification of three lung cancer types alongside normal lung tissue (adenocarcinoma, large cell carcinoma, normal, and squamous cell carcinoma) using CT images. The proposed methodology combines contrast-limited adaptive histogram equalization (CLAHE) and Gaussian blur to enhance image quality, reduce noise, and improve visual clarity. The LPDCNN extracts discriminant features while minimizing computational complexity (0.53 million parameters and 9 layers). The Ridge-ELM model was developed to enhance classification performance, replacing the traditional pseudoinverse in the ELM approach. Through comprehensive evaluation against state-of-the-art models, the framework achieves remarkable average recall and accuracy values of 98.25 ± 1.031 % and 98.40 ± 0.822 %, respectively, through rigorous five-fold cross-validation for four-class classifications. In binary classifications, outstanding results are obtained with recall and accuracy values of 99.70 ± 0.671 % and 99.70 ± 0.447 %%, respectively. Notably, the framework exhibits exceptional efficiency, with a testing time of only 0.003 s. Additionally, integrating the SHAP (Shapley Additive Explanations) in the proposed framework enhances Explain-ability, providing insights into decision-making and boosting confidence in real-world lung cancer diagnoses. [ABSTRACT FROM AUTHOR]