Back to Search Start Over

Liver Transplantation for Hepatocellular Carcinoma: A Narrative Review and A Glimpse into The Future.

Authors :
Liu, Hao
Sethi, Vrishketan
Li, Xingjie
Xiao, Yao
Humar, Abhinav
Source :
Seminars in Liver Disease. Feb2024, Vol. 44 Issue 1, p79-98. 20p.
Publication Year :
2024

Abstract

This document provides a comprehensive overview of liver transplantation for hepatocellular carcinoma (HCC) and explores various factors that impact patient outcomes. It discusses the evolution of selection criteria and organ allocation policies, as well as advancements in targeted therapy and the use of living donor liver transplants. The document also examines the challenges of predicting post-transplant survival outcomes and the potential of biomarkers to predict HCC recurrence. It discusses the current liver allocation system in the United States and the need to balance utility and urgency in transplant allocation policies. The document also explores locoregional therapy and systemic therapies for managing HCC, as well as the potential use of immune checkpoint inhibitors. It concludes by emphasizing the need for innovative strategies and advancements in transplant surgery to improve patient outcomes in the future. [Extracted from the article]

Details

Language :
English
ISSN :
02728087
Volume :
44
Issue :
1
Database :
Academic Search Index
Journal :
Seminars in Liver Disease
Publication Type :
Academic Journal
Accession number :
176635339
Full Text :
https://doi.org/10.1055/a-2242-7543