Back to Search
Start Over
Effect of experimental dentin etchants on dentin bond strength, metalloproteinase inhibition, and antibiofilm activity.
- Source :
-
Dental Materials . Apr2024, Vol. 40 Issue 4, pe12-e23. 12p. - Publication Year :
- 2024
-
Abstract
- this study evaluated dentin microtensile bond strength (µTBS) and failure modes (at 24 h and one year), bonding interface regarding hybridization, surface morphology regarding demineralization, in situ metalloproteinase (MMP) activity, and antibacterial effect of three dentin etchants compared to 35% phosphoric acid (PA). The Adper Single Bond 2 adhesive (3 M Oral Care) was applied on moist dentin etched with PA (control) or on air-dried dentin etched with 3% aluminum nitrate + 2% oxalic acid (AN), 6.8% ferric oxalate + 10% citric acid (FO), or 10% citric acid (CA). The µTBS test used 40 human teeth (n = 10). Failure modes and surface morphology were analyzed by scanning electron microscopy (n = 3), while bonding interface morphology and MMP activity were evaluated by laser scanning confocal microscopy (n = 3). Antibacterial activity was evaluated against S. Mutans biofilm by means of viable cells count (CFU/mL). PA presented the highest bond strengths regardless of aging time. PA, AN, and CA showed stable bond strengths after one year of storage. Adhesive and mixed failures were predominant in all groups. Thin hybrid layers with short resin tags were observed for the experimental etchants. The AN-based etchant was able to inhibit MMP activity. All tested etchants presented antibacterial activity against S. Mutans biofilm. This study suggests different dentin etchants capable of inhibiting MMP activity while also acting as cavity disinfectants. • Phosphoric acid bond strength was higher than the tested etchants. • Ferric oxalate + citric acid showed significant bond strength reduction at 1 year. • Gelatinolytic activity was inhibited by aluminum nitrate + oxalic acid. • Bacteria cell viability was reduced according to the pH of the acids. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DENTAL adhesives
*BOND strengths
*ETCHING reagents
*DENTIN
*OXALIC acid
*CITRIC acid
Subjects
Details
- Language :
- English
- ISSN :
- 01095641
- Volume :
- 40
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Dental Materials
- Publication Type :
- Academic Journal
- Accession number :
- 176543459
- Full Text :
- https://doi.org/10.1016/j.dental.2024.02.017