Cytotoxic potential and phytochemical profiling of Scurrula atropurpurea (Bl.) dans extracts on T47D cell line.

The parasitic plant (Scurrula atropurpurea (Bl.) Dans) is well-known for treating diuretic, mitotic, and cancerous conditions. It grows on trees such as those bearing tea, mangoes, and avocados. This study evaluated the activity of ethyl acetate and ethanol extracts of S. atropurpurea (growing on avocado trees) using the MTT assay on the T47D breast cancer cell line. Soxhletation was performed with ethyl acetate and re-extraction of the residue with ethanol. The ethyl acetate extract of a phytochemical analysis using the TLC method exhibited four peaks, while the ethanol extract contained six peaks. According to the findings of the study, the IC50 of the ethyl acetate and ethanol extract was 17.93 and 44.64 µg/mL, respectively. Ethyl acetate has the highest potential as a cytotoxic agent than ethanol extract. [ABSTRACT FROM AUTHOR]