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Cocrystallization for Improving Anticancer Activity of Drugs.
- Source :
-
Crystal Research & Technology . Apr2024, Vol. 59 Issue 4, p1-9. 9p. - Publication Year :
- 2024
-
Abstract
- Cocrystallization can change the physicochemical and pharmacokinetic properties of active pharmaceutical ingredients (API) and improve biological activities. This study focuses on the documented biological activities of APIs in cocrystal form, specifically those with anticancer properties. Additionally, the mechanisms by which these APIs exhibit modified anticancer effects are discussed. Generally, this technique can change anticancer activity through solubilization, enhancing dissolution rate, permeability improvement, stabilization, producing a slow‐release form, and retaining transient in solution and interaction with receptors. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02321300
- Volume :
- 59
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Crystal Research & Technology
- Publication Type :
- Academic Journal
- Accession number :
- 176495977
- Full Text :
- https://doi.org/10.1002/crat.202300253