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Barley MLA3 recognizes the host-specificity effector Pwl2 from Magnaporthe oryzae.
- Source :
-
Plant Cell . Feb2024, Vol. 36 Issue 2, p447-470. 24p. - Publication Year :
- 2024
-
Abstract
- Plant nucleotide-binding leucine-rich repeat (NLRs) immune receptors directly or indirectly recognize pathogen-secreted effector molecules to initiate plant defense. Recognition of multiple pathogens by a single NLR is rare and usually occurs via monitoring for changes to host proteins; few characterized NLRs have been shown to recognize multiple effectors. The barley (Hordeum vulgare) NLR gene Mildew locus a (Mla) has undergone functional diversification, and the proteins encoded by different Mla alleles recognize host-adapted isolates of barley powdery mildew (Blumeria graminis f. sp. hordei [Bgh]). Here, we show that Mla3 also confers resistance to the rice blast fungus Magnaporthe oryzae in a dosage-dependent manner. Using a forward genetic screen, we discovered that the recognized effector from M. oryzae is Pathogenicity toward Weeping Lovegrass 2 (Pwl2), a host range determinant factor that prevents M. oryzae from infecting weeping lovegrass (Eragrostis curvula). Mla3 has therefore convergently evolved the capacity to recognize effectors from diverse pathogens. MLA3 confers dosage-dependent resistance to rice blast through recognition of the effector Pwl2, which contributes to host range dynamics. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10404651
- Volume :
- 36
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Plant Cell
- Publication Type :
- Academic Journal
- Accession number :
- 176449146
- Full Text :
- https://doi.org/10.1093/plcell/koad266