Back to Search
Start Over
Epidural analgesia during surgery and its relation to postoperative myocardial infarction: meta-analysis.
- Source :
-
Videosurgery & Other Miniinvasive Techniques / Wideochirurgia i Inne Techniki Mało Inwazyjne . Mar2024, Vol. 19 Issue 1, p11-24. 14p. - Publication Year :
- 2024
-
Abstract
- Introduction: Epidural analgesia has been studied for its potential advantages after surgery in a number of randomized clinical trials, with most finding improvements in pain and secondary endpoints like the incidence of postoperative complications. Aim: To assess the relationship between use of epidural analgesia and adverse cardiac outcomes expressed by myocardial infarction (MI). Material and methods: Fifty-three studies were recruited to quantify the influence of different surgical-related analgesic methods on clinical parameters (mortality and adverse events). The results of these trials were analysed using a random effects model, which was then used to calculate the mean difference (MD) with 95 per cent confidence intervals (CIs). Results: Epidural analgesia resulted in preferred cardiac outcomes compared with traditional analgesia. These findings were supported by significantly lower MI events for the epidural analgesia group as follows: p = 0.005, p = 0,007, and p = 0.03 for the total number of included studies, studies with high risk of bias, and studies with low risk of bias, respectively. Studies with intermediate risk showed a non-significant difference between both groups (p = 0.7). Conclusions: Epidural analgesia has a significant protective cardiac effect through the reduction of postoperative MI events among surgery subjects. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MYOCARDIAL infarction
*EPIDURAL analgesia
*RANDOM effects model
*CLINICAL trials
Subjects
Details
- Language :
- English
- ISSN :
- 18954588
- Volume :
- 19
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Videosurgery & Other Miniinvasive Techniques / Wideochirurgia i Inne Techniki Mało Inwazyjne
- Publication Type :
- Academic Journal
- Accession number :
- 176420257
- Full Text :
- https://doi.org/10.5114/wiitm.2024.135977