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Palladium‐Catalyzed Cyclization/Alkenylation of Ynone Oximes with Vinylsilanes for the Assembly of Isoxazolyl Vinylsilanes.
- Source :
-
Chemistry - An Asian Journal . Mar2024, Vol. 19 Issue 6, p1-7. 7p. - Publication Year :
- 2024
-
Abstract
- A palladium‐catalyzed cascade cyclization/alkenylation for the assembly of synthetically valuable isoxazolyl vinylsilane derivative has been accomplished. Easily accessible ynone oximes, and available vinylsilane agents were used as the reaction starting materials This protocol features broad substrate scope, good functional group tolerance, and good step‐ and atom‐economy. Remarkably, this approach provides a new approach for the construction of structurally diverse isoxazolyl‐containing vinylsilanes with high molecular complexity, showing a promising application in synthetic and pharmaceutical chemistry. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18614728
- Volume :
- 19
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Chemistry - An Asian Journal
- Publication Type :
- Academic Journal
- Accession number :
- 176294702
- Full Text :
- https://doi.org/10.1002/asia.202301122