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Oral Chronic Graft-versus-Host Disease in Post-Hematopoietic Stem Cell Transplant Patients Following SARS-CoV-2 Vaccination: Case Reports.
- Source :
-
Case Reports in Oncology . 2023, Vol. 16 Issue 1, p1287-1292. 6p. - Publication Year :
- 2023
-
Abstract
- Patients receiving allogeneic hematopoietic stem cell transplant may experience graft-versus-host disease (GVHD) in which donor immune cells cause an immune reaction in host tissues. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines are highly effective in prevention of severe coronavirus-2019 (COVID-19) disease, but the vaccine can result in immune activation and GVHD. Herein, we report 4 cases of oral manifestations that may have been stimulated by COVID-19 or vaccination with Pfizer or Moderna vaccines. We believe this study is the first to report oral changes driven by an inflammatory/immune mechanism leading to oral symptomatic cGVHD. The clinical impact of this study is early recognition and appropriate management of oral symptomatic cGVHD following COVID-19 disease or SARS-CoV-2 vaccination. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16626575
- Volume :
- 16
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Case Reports in Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 176273319
- Full Text :
- https://doi.org/10.1159/000533821