儿童眼眶占位性病变287例临床分布特征分析.

Objective To investigate the classification and distribution features of orbital space-occupying diseases in children. Methods A retrospective case series study was conducted. The clinical data of 287 pediatric patients with orbital space-occupying diseases admitted to the Department of Ophthalmology at the Second Affiliated Hospital of the Air Force Military Medical University from January 2012 to June 2022 were collected. According to the Shields classification method, the benign and malignant orbital diseases were classified by gender and age, and the classification and distribution features of these diseases were analyzed. Results Among 287 children with orbital space-occupying diseases, 91.29% were benign diseases and 8.71% were malignant diseases. Benign diseases mainly included cystic lesions, vascular lesions, neurogenic tumors, among which dermoid cysts were the most common. The malignant diseases mainly consisted of myogenic tumors and lymphohematopoietic system tumors, among which rhabdomyosarcoma was the most common. Orbital space-occupying lesions in children were mostly found in 0-4 years old, and the incidence rate of dermoid cysts and capillary hemangiomas was significantly correlated with age (P<0.05). The correlation between the nature of the lesion and gender is not significant, however, Langerhans cell histiocytosis, dermoid cysts, capillary hemangiomas, and rhabdomyosarcoma were more common in male patients. Conclusions The clinical distribution pattern of orbital space-occupying diseases in children is different from that observed in adults, it is mainly composed of congenital and embryonic diseases. Benign lesions are predominantly characerized by dermatoid cysts while rhabdomyosarcoma prevails among malignant cases. Certain diseases exhibit distinct age or gender predilections. [ABSTRACT FROM AUTHOR]