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In situ formation of solid-supported lipid/DNA complexes

Authors :
Caracciolo, Giulio
Amenitsch, Heinz
Sadun, Claudia
Caminiti, Ruggero
Source :
Chemical Physics Letters. Apr2005, Vol. 405 Issue 4-6, p252-257. 6p.
Publication Year :
2005

Abstract

Abstract: Solid-supported lipid/DNA complexes were prepared by using highly aligned 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) multibilayers as a template. The complex formation was promoted in situ and followed in time. The resulting DOTAP/DNA complex shows a good degree of orientation along the normal to the support as revealed by combined time-resolved energy dispersive X-ray diffraction (EDXD) and surface synchrotron small angle X-ray scattering (SAXS) measurements. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00092614
Volume :
405
Issue :
4-6
Database :
Academic Search Index
Journal :
Chemical Physics Letters
Publication Type :
Academic Journal
Accession number :
17624081
Full Text :
https://doi.org/10.1016/j.cplett.2005.02.047