Pregnancy Outcome in Eisenmenger Syndrome at an Indian Tertiary Center.

Aim: To evaluate the materno-fetal outcome of pregnancy with Eisenmenger syndrome (ES). Materials and methods: This retrospective observational study was carried out at a tertiary teaching institute over a 1-year period. The occurrence of ES in pregnant women with the cardiac disease along with their materno-fetal outcomes was analyzed. Results: Among 27,259 antenatal women who delivered over a period of 1 year, 104 had cardiac disease with 31 congenital heart disease (CHD). Only three cases of pregnancies with ES were found among 104. Thus, ES was seen in 1:9086 pregnant women, 1:35 pregnant women with cardiac disorders, and 1:10 pregnant women with CHD. The mean age was 25.3 ± 0.58 years while the mean gestational age (GA) at delivery was 35.23 ± 0.67 weeks. The mean pulmonary arterial pressure was 68.7 ± 13.3 mm Hg. All had preterm deliveries. Vaginal delivery was conducted in 66.7% while 33.3% had a cesarean delivery. No maternal mortality was seen. Fetal demise was seen in one of three cases. Conclusion: Multidisciplinary care with the availability of a critical care unit can help achieve a positive materno-fetal outcome in ES during pregnancy which till now has been known to have a very high mortality rate. Clinical significance: Of all CHD in pregnancy, ES is associated with a very high maternal mortality rate. However, with multidisciplinary effort and approach, optimum outcomes are achievable. [ABSTRACT FROM AUTHOR]