Next-Generation Public Health Genomics: A Call to Assess the Equitable Implementation, Population Health Impact, and Sustainability of Precision Public Health Applications.

The field of Public Health Genomics has expanded beyond newborn screening to other applications that have the potential to improve public health. However, there is a need to measure the population health impact and sustainability of these applications, as well as address concerns about access and health inequities. Implementation science, which focuses on integrating evidence-based practices into public health settings, can inform the best approaches for realizing the promise of public health genomics. The implementation of population genetic screening (PGS) is used as an example to illustrate the different phases of implementation research, including exploration, planning, implementation, and sustainment. The current literature on public health genomics is primarily focused on the exploration and planning phases, with limited research on population health outcomes and sustainability. To advance the field, there is a need for multidisciplinary collaboration, standardized evaluation metrics, and capacity building in public health genomics research. [Extracted from the article]