The dual effects of miR-222 in cardiac hypertrophy: bridging pathological and physiological paradigms.

This article discusses the dual effects of miR-222 in cardiac hypertrophy, specifically examining the differences between physiological and pathological hypertrophy. The study highlights the role of miR-222 in regulating pathways in both forms of hypertrophy and its potential as a therapeutic target. The article also emphasizes the context-dependent nature of miRNA function in cardiac growth and the need for precision in targeting miRNAs for therapeutic purposes. Overall, the study enhances our understanding of the molecular mechanisms underlying heart disease and provides new avenues for therapeutic exploration. [Extracted from the article]