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A facile, regio and diastereoselective synthesis of functionalized azetidin-2-ones: Cu(I) mediated Kinugasa reaction of functionalized nitrones with acetylenic alcohols.
- Source :
-
Synthetic Communications . 2024, Vol. 54 Issue 7, p583-591. 9p. - Publication Year :
- 2024
-
Abstract
- The manuscript presents an efficient method for the synthesis of various cis-azetidin-2-ones with high regio- and diastereoselectivity. This approach utilizes Kinugasa reaction involving diverse functionalized nitrones, including diaryl nitrones and α,β-unsaturated nitrones, in conjunction with acetylenic alcohols. Copper (I) serves as a catalyst to facilitate the transformation. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NITRONES
*COPPER
*ISOXAZOLIDINES
*MANUSCRIPTS
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 54
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 176071693
- Full Text :
- https://doi.org/10.1080/00397911.2024.2321596