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Current Strategies on the Enantioselective Synthesis of Modified Nucleosides.

Authors :
Mondal, Samir Kumar
Mahto, Birkishore
Pal, Shantanu
Chandra, Girish
Source :
Synlett. Apr2024, Vol. 35 Issue 6, p616-634. 19p.
Publication Year :
2024

Abstract

This article provides an overview of the current strategies for the enantioselective synthesis of modified nucleosides, which have been used in the treatment of various diseases, including viruses. The focus is on the modifications that can be made to different parts of the nucleoside structure to create therapeutically useful compounds. The article discusses the latest developments in the synthesis of cyclic and acyclic nucleosides, highlighting various methods and reactions that can be used to achieve high yields and enantioselectivities. The authors also acknowledge the institutions that supported their research. [Extracted from the article]

Details

Language :
English
ISSN :
09365214
Volume :
35
Issue :
6
Database :
Academic Search Index
Journal :
Synlett
Publication Type :
Academic Journal
Accession number :
176011026
Full Text :
https://doi.org/10.1055/a-2212-8502