Mechanochemistry-based liquid-assisted synthesis of hydrophobic Zr-Beta with high metal loading for Meerwein-Ponndorf-Verley reduction.

[Display omitted] • Rapid crystallization of Zr-Beta with high Zr content possible with MCLA protocol. • Zr-Beta formed with high crystallinity and hydrophobicity. • High Zr loadings useful in MPV reduction of sterically hindered ketones and diones. • MCLA-synthesized Zr-Beta is less susceptible to poisoning by water adsorption. Heteroatom-incorporated zeolite catalysts are critical for biomass utilization and feedstock valorization in green chemistry. Key features are adjustable acidity, high stability, and a tailored range of functionalities. However, an environmentally benign synthesis of zeolites with good crystallinity and especially with high levels of metal substitution into the lattice remains challenging. Here, we propose a mechanochemistry-based liquid-assisted method (MCLA) for Zr-incorporated Beta zeolites that is high yielding, facile and sustainable. Compared with the fluoride-mediated hydrothermal method, crystallization times were considerably shortened so that Si-Beta and Zr-Beta (Si/Zr 100) zeolites can be synthesized within 9 and 15 h, respectively. Using the MCLA route, Beta zeolites with Zr loading up to 10.4 wt% (Si/Zr 12.5) were obtained. The materials have excellent catalytic activity for Meerwein-Ponndorf-Verley reductions with much higher water tolerance compared to Zr-Beta prepared by the post-synthesis method. The hydrophobic nature of the MCLA-synthesized zeolites makes them particularly useful as catalysts for organic reactions. [ABSTRACT FROM AUTHOR]