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Evaluation of serum micro 155 in breast cancer.

Authors :
Jaber, Haider Yahya
Ali, Angham Jasim Mohmmed
Source :
AIP Conference Proceedings. 2024, Vol. 3092 Issue 1, p1-8. 8p.
Publication Year :
2024

Abstract

MicroRNA 155 (miR-155) play a criticals role in controlling the evolution and vital tasks of different immune-cells. We have previously shown that miR 155 is essential for dendritic cells' (DCs') ability to organize themselves in breast cancer instances. Lack of MIR155 in dendritic cells compromised their capacity to stimulate T lymphocytes., maturation, cytokine production, and migration. Objectives: The purpose of this investigation is to determine how autoantibody micro155 relates to breast cancer in women. Methods: The oncologist at the Imam Al-Sadiq General Teaching Hospital in Iraq-Babylon gathered medical data from (130) participants and divided the subjects into case and control groups based on predetermined criteria. The demographic study also included age, education, marital status, laboratory results, and signs and symptoms. From September to December 2022, micro 155 levels are assess by real-time Polymerase Chain reaction (RT-PCR) - We detected and determined the number of nitrogenous bases in a single primer used to measure the plasma micro 155 gene expiration. Results: Highly significant variations in micro155 between women suffering from breast cancer than to the control groups, which was revealed in the results. Micro155 level women breast cancer (5.49194492±.944835955) whereas the control group appears (1.00000 ±.0000000). Conclusion: Through the current study, we found that (MIR155) in (cases) women with breast cancer was higher (5.4) than in unaffected women (1.0000), and this is considered MIR155 as biomarker for in breast cancer women. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0094243X
Volume :
3092
Issue :
1
Database :
Academic Search Index
Journal :
AIP Conference Proceedings
Publication Type :
Conference
Accession number :
175939810
Full Text :
https://doi.org/10.1063/5.0200442