Introduction: Synthetic Biology for Cancer Immunology Special Issue.

This article discusses the use of synthetic biology in cancer immunology, specifically focusing on adoptive T-cell therapy and phototherapy as potential treatments for cancer. The first review explores ways to enhance the antitumor effects of CAR-T cells through cytokine signaling. The second review introduces near-infrared photoimmunotherapy (NIR-PIT) as a promising cancer phototherapy technique. The third review discusses the challenges and potential solutions in using allogeneic cells for cell therapy. The final review explores the unique metabolism of regulatory T cells in the tumor microenvironment and how it can be targeted for immunotherapy. [Extracted from the article]