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An unusual phenocopy for postmenopausal ovarian hyperandrogenism: LH‐driven testosterone secretion by adrenal adenoma expressing luteinising hormone‐chorionic gonadotrophin receptor.

Authors :
Ali, Mudassir
Rai, Ashutosh
Howarth, Sophie
Madathil, Asgar
Rice, Tom
Boot, Christopher
Quinton, Richard
Korbonits, Márta
Mamoojee, Yaasir H.
Source :
Clinical Endocrinology. Apr2024, Vol. 100 Issue 4, p328-331. 4p.
Publication Year :
2024

Abstract

This article presents a rare case of postmenopausal hyperandrogenism, which is characterized by an excess of male hormones in women after menopause. The condition can be caused by various factors, including ovarian or adrenal neoplasia, Cushing's syndrome, or polycystic ovary syndrome. The article emphasizes the importance of thorough endocrine investigation and diagnostic tools such as serum hormone levels, imaging, and venous sampling. The case study discussed in the article highlights the challenges in diagnosing and localizing the source of hyperandrogenism and suggests the potential usefulness of venous sampling in certain patients. The study was conducted by a team of medical professionals, including radiologists, a histopathologist, an endocrine surgeon, and a gynecologist. [Extracted from the article]

Details

Language :
English
ISSN :
03000664
Volume :
100
Issue :
4
Database :
Academic Search Index
Journal :
Clinical Endocrinology
Publication Type :
Academic Journal
Accession number :
175870301
Full Text :
https://doi.org/10.1111/cen.15019