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Impact of COVID-19 Medication (Favipiravir and Hydroxychloroquine) on High Frequency Hearing.
- Source :
-
Indian Journal of Otolaryngology & Head & Neck Surgery . Feb2024, Vol. 76 Issue 1, p899-903. 5p. - Publication Year :
- 2024
-
Abstract
- During the initial phase of the COVID-19 pandemic, there was ongoing investigation into potentially effective treatments. Antiviral medications such as Favipiravir and Hydroxychloroquine were employed to treat COVID-19 infections. However, limited studies have examined the adverse effects of these medications on hearing, particularly at extended high frequencies. This study included 10 subjects who had received medications like Azithromycin, a combination of Favipiravir and Hydroxychloroquine, and Hydroxychloroquine alone as part of their COVID-19 treatment. These subjects had previously undergone extended high-frequency audiometry testing (from 8 to 20 kHz) as part of another project conducted by the same department before contracting COVID-19. Post-COVID-19 extended high-frequency audiometry was performed 1 month after the patients received a negative RT-PCR report. The results were then compared using a Paired t-test. A significant shift in the thresholds of high frequencies above 8–20 kHz is found in subjects who had received Favipiravir and Hydroxychloroquine medications. We observed a significant impact of COVID-19 medications on high-frequency hearing, which tends to go unnoticed in regular pure-tone audiometry evaluations. Therefore, our study emphasizes the need for regular follow-ups, including detailed audiological assessments that incorporate extended high-frequency testing, at least once every 3 months for patients who have taken medications for COVID-19 treatment. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDROXYCHLOROQUINE
*COVID-19
*COVID-19 treatment
*COVID-19 pandemic
*DRUGS
Subjects
Details
- Language :
- English
- ISSN :
- 22313796
- Volume :
- 76
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Otolaryngology & Head & Neck Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 175826016
- Full Text :
- https://doi.org/10.1007/s12070-023-04313-z