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Renal angina index for early identification of risk of acute kidney injury in critically ill children.

Authors :
Alves, Marina T. B.
Iglesias, Simone B. O.
Koch Nogueira, Paulo C.
Source :
Pediatric Nephrology. Apr2024, Vol. 39 Issue 4, p1245-1251. 7p.
Publication Year :
2024

Abstract

Background: The main objective was to test whether the Renal Angina Index (RAI), calculated on patient admission to the pediatric intensive care unit (PICU), is associated with the risk of acute kidney injury (AKI) based on the Kidney Disease: Improving Global Outcomes (KDIGO) (stage ≥ 2) in 72 h. The specific aim was to analyze the performance of the RAI at a specialized oncology PICU. Methods: Retrospective cohort study involving two pediatric intensive care units located within a general hospital and an oncology hospital. Children aged ≥ 3 months to < 18 years admitted to the intensive care units in 2017 with a length of stay ≥ 72 h were included. Results: The sample included 249 patients, of which 51% were male (127 patients), with median age of 77 months, and mean ICU stay of 5 days. Of the total admissions, 141 were clinical (57%) and 108 surgical. The rate of AKI was 15% and death rate within 30 days was 13%. Having a positive RAI on admission showed a statistically significant association with AKI at Day 3 (OR = 18.5, 95%CI = 4.3 – 78.9, p < 0.001) and with death (OR = 3.9, 95%CI = 1.6 – 9.9, p = 0.004). The accuracy of the RAI in the cancer population was 0.81 on the ROC curve (95%CI 0.74, 0.88). Conclusions: The RAI is a useful tool for predicting AKI and death in critically ill children, including in oncology units. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0931041X
Volume :
39
Issue :
4
Database :
Academic Search Index
Journal :
Pediatric Nephrology
Publication Type :
Academic Journal
Accession number :
175695425
Full Text :
https://doi.org/10.1007/s00467-023-06170-y