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NOD样受体蛋白3(NLRP3)炎性小体在肝细胞癌发生发展中的 作用.

Authors :
余学海
陈本栋
刘伊敏
马勇新
张旭升
周红才
马海燕
Source :
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi. Feb2024, Vol. 40 Issue 2, p397-401. 5p.
Publication Year :
2024

Abstract

In recent years, NOD-like receptor protein 3 (NLRP3) inflammasome in tumors has become a research hotspot, especially in melanoma, colorectal cancer, lung cancer, and breast cancer, and more and more evidence has shown that inflammation plays a role in the development, progression, angiogenesis, and invasion of cancer. Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and there are still controversies over the role of NLRP3 inflammasome in the development and progression of HCC. Therefore, this article reviews the potential impact of NLRP3 inflammasome in the progression of HCC and its mechanism of action in anticancer therapy, and it is believed that NLRP3 inflammasome can be used as an effective therapeutic target for HCC patients. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
10015256
Volume :
40
Issue :
2
Database :
Academic Search Index
Journal :
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi
Publication Type :
Academic Journal
Accession number :
175657918
Full Text :
https://doi.org/10.12449/JCH240229