Cardiac indices of driver fatigue across in-lab and on-road studies.

Driver fatigue is a major contributor to road accidents. Therefore, driver assistance systems (DAS) that would monitor drivers' states may contribute to road safety. Such monitoring can potentially be achieved with input from ECG indices (e.g., heart rate). We reviewed the empirical literature on responses of cardiac measures to driver fatigue and on detecting fatigue with cardiac indices and classification algorithms. We used meta-analytical methods to explore the pooled effect sizes of different cardiac indices of fatigue, their heterogeneity, and the consistency of their responses across studies. Our large pool of studies (N = 39) allowed us to stratify the results across on-road and simulator studies. We found that despite the large heterogeneity of the effect sizes between the studies, many indices had significant pooled effect sizes across the studies, and more frequently across the on-road studies. We also found that most indices showed consistent responses across both on-road and simulator studies. Regarding the detection accuracy, we found that even on-road classification could have been as accurate as 70% with only 2-min of data. However, we could only find two on-road studies that employed fatigue classification algorithms. Overall, our findings are encouraging with respect to the prospect of using cardiac measures for detecting driver fatigue. Yet, to fully explore this possibility, there is a need for additional on-road studies that would employ a similar set of cardiac indices and detection algorithms, a unified definition of fatigue, and additional levels of fatigue than the two fatigue vs alert states. • We reviewed 39 empirical papers on cardiac correlates of fatigue in-lab and on-road. • Significant pooled effect sizes and consistency were found both in-lab and on-road. • Highest fatigue detection was in-lab but still fairly accurate and fast on-road. [ABSTRACT FROM AUTHOR]