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Long-Chain Omega-3 Fatty Acid Supplementation and Exercise-Induced Muscle Damage: EPA or DHA?
- Source :
-
Medicine & Science in Sports & Exercise . Mar2024, Vol. 56 Issue 3, p476-485. 10p. - Publication Year :
- 2024
-
Abstract
- Purpose: Long-chain omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) may enhance recovery from exercise-induced muscle damage (EIMD). However, it is unclear if the effects are due to EPA, DHA, or both. The purpose of this investigation was to examine the effect of EPA + DHA, EPA, and DHA compared with placebo (PL) on muscular recovery. Methods: Thirty males were randomized to 4 g·d−1 EPA + DHA (n = 8), EPA (n = 8), DHA (n = 7), or PL (n = 7). After 7-wk supplementation, a downhill running (20 min, 70% V̇O2max, −16% gradient) plus jumping lunges (5 × 20 reps, 2-min rest intervals) muscle damage protocol was performed. Indices of muscle damage, soreness, muscle function, and inflammation were measured at baseline and throughout recovery. The omega-3 index (O3i; %EPA + %DHA in erythrocytes) was used to track tissue EPA and DHA status. Results: After supplementation, the O3i was significantly higher than PL in all experimental groups (P < 0.001). Leg press performance was lower in the PL group at 24 h compared with EPA (P = 0.019) and at 72 h for EPA (P = 0.004) and DHA (P = 0.046). Compared with PL, muscle soreness was lower in the DHA (P = 0.015) and EPA (P = 0.027) groups at 48 h. Albeit nonsignificant, EPA + DHA tended to attenuate muscle soreness (d = 1.37) and leg strength decrements (d = 0.75) compared with PL. Jump performance and power metrics improved more rapidly in the EPA and DHA groups (time effects: P < 0.001). Measures of inflammation, range of motion, and muscle swelling were similar between groups (P > 0.05). Conclusions: Compared with PL, 4 g·d−1 of EPA or DHA for 52 d improves certain aspects of recovery from EIMD. EPA + DHA did not clearly enhance recovery. Equivalent dosing of EPA + DHA may blunt the performance effects observed in EPA or DHA alone. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SKELETAL muscle physiology
*DOCOSAHEXAENOIC acid
*BIOMARKERS
*C-reactive protein
*BODY composition
*AEROBIC capacity
*STATISTICS
*MYALGIA
*RUNNING
*RANGE of motion of joints
*PHOTON absorptiometry
*ANALYSIS of variance
*INFLAMMATION
*SELF-perception
*OXYGEN consumption
*ANTHROPOMETRY
*SERUM
*CREATINE kinase
*BLOOD collection
*VISUAL analog scale
*MUSCLE strength testing
*DIETARY supplements
*EICOSAPENTAENOIC acid
*COOLDOWN
*RANDOMIZED controlled trials
*EXERCISE intensity
*FISHES
*QUESTIONNAIRES
*DESCRIPTIVE statistics
*REPEATED measures design
*BLIND experiment
*RESEARCH funding
*STATISTICAL sampling
*JUMPING
*MYOSITIS
*URINALYSIS
*BIOMECHANICS
*DATA analysis software
*DATA analysis
Subjects
Details
- Language :
- English
- ISSN :
- 01959131
- Volume :
- 56
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Medicine & Science in Sports & Exercise
- Publication Type :
- Academic Journal
- Accession number :
- 175500807
- Full Text :
- https://doi.org/10.1249/MSS.0000000000003332