Synthesis and characterization PEG4000 - Graphene oxide nanosheets – Black seed extraction as anticancer therapy.

Drug delivery system, preparation by conjugation of graphene oxide nanosheets (GONSs) and polyethylene glycol (PEG4000) 4000 then loading with Nigella sativa (N. sativa) (black seed extraction), drug. X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy (TEM) were used to characterize the material. XRD peaks indicate the successful synthesis of GONSs with a hexagonal structure, while in GONSs –PEG4000, the site shifted, ensuring the capped of two materials. Flaky wavy sheet with tree branch exhibited in TEM images with particles size ± ∼100 nm. The anticancer activity study in vitro for two lines of cancerous tissue AMJ13 and SK-GT-4 cells. Drug nanoparticles with plant extraction show a Cytotoxic high effect than nanoparticles. [ABSTRACT FROM AUTHOR]