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Successful Treatment of Recurrent Lymphocytic Hypophysitis with Fractionated Stereotactic Radiotherapy: A Single-Center Experience and Systematic Literature Review.

Authors :
Khaleghi, Mehdi
Finger, Guilherme
Wu, Kyle
Munjal, Vikas
Ghalib, Luma
Kobalka, Peter
Blakaj, Dukagjin
Carrau, Ricardo
Prevedello, Daniel
Source :
Journal of Neurological Surgery. Part B. Skull Base. 2024 Supplement, Vol. 85, pS1-S398. 398p.
Publication Year :
2024

Abstract

This article discusses the successful treatment of recurrent lymphocytic hypophysitis (LH) using fractionated stereotactic radiotherapy (FSRT). LH is a rare autoimmune inflammation of the pituitary gland that can mimic pituitary adenomas. The authors conducted a systematic literature review and found that FSRT can be a viable alternative treatment for refractory cases of LH. The study included eight patients, and seven of them achieved a complete clinical response after one course of radiation. FSRT offers long-term disease control while minimizing radiation exposure to nearby critical structures. However, further studies are needed to determine the long-term effects, optimal dose planning, and patient selection criteria for FSRT. [Extracted from the article]

Details

Language :
English
ISSN :
21936331
Volume :
85
Database :
Academic Search Index
Journal :
Journal of Neurological Surgery. Part B. Skull Base
Publication Type :
Academic Journal
Accession number :
175285566
Full Text :
https://doi.org/10.1055/s-0044-1779975