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Physical activity intensity and markers of inflammation in those with non-alcoholic fatty liver disease.
- Source :
-
Diabetes Research & Clinical Practice . Jan2024, Vol. 207, pN.PAG-N.PAG. 1p. - Publication Year :
- 2024
-
Abstract
- To investigate associations between objectively measured light (LPA) and moderate-to-vigorous (MVPA) physical activity on plasma homocysteine and serum C-reactive protein (CRP) in individuals with Non-Alcoholic Fatty Liver Disease (NAFLD). METHODS: This study was a secondary analysis using data from 2003 to 2006 National Health and Nutrition Examination Survey including a total of 983 individuals with NAFLD. Physical activity was assessed over 7 days with accelerometers. Participants were split into tertiles based on average daily minutes of LPA or MVPA and CRP and homocysteine were assessed across tertiles. RESULTS: Adjusted plasma homocysteine and CRP were not different between groups regarding levels of LPA (Homocysteine: 1st tertile – 10.4 ± 0.7 µmol/L; 2nd tertile – 9.6 ± 0.4 µmol/L; 3rd tertile – 9.6 ± 0.4 µmol/L; p = 0.28; CRP: 1st tertile – 0.79 ± 0.12 mg/dL; 2nd tertile – 0.73 ± 0.09 mg/dL; 3rd tertile – 0.73 ± 0.09 mg/dL; p = 0.72). Adjusted CRP was significantly (p = 0.02) different across MVPA tertiles (1st: 0.87 ± 0.13 mg/dL; 2nd: 0.75 ± 0.10 mg/dL; 3rd:0.65 ± 0.09). CONCLUSIONS: LPA does not appear to be effective at improving homocysteine or CRP levels in individuals with NAFLD. However, MVPA may be an effective therapy for decreasing CRP in NAFLD patients. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01688227
- Volume :
- 207
- Database :
- Academic Search Index
- Journal :
- Diabetes Research & Clinical Practice
- Publication Type :
- Academic Journal
- Accession number :
- 175276862
- Full Text :
- https://doi.org/10.1016/j.diabres.2023.111047