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Dissecting the biophysics and biology of intrinsically disordered proteins.
- Source :
-
Trends in Biochemical Sciences . Feb2024, Vol. 49 Issue 2, p101-104. 4p. - Publication Year :
- 2024
-
Abstract
- Intrinsically disordered regions (IDRs) within human proteins play critical roles in cellular information processing, including signaling, transcription, stress response, DNA repair, genome organization, and RNA processing. Here, we summarize current challenges in the field and propose cutting-edge approaches to address them in physiology and disease processes, with a focus on cancer. Intrinsically disordered regions (IDRs) within human proteins play critical roles in cellular information processing, including signaling, transcription, stress response, DNA repair, genome organization, and RNA processing. Here, we summarize current challenges in the field and propose cutting-edge approaches to address them in normal physiology and disease, with a focus on cancer. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09680004
- Volume :
- 49
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Trends in Biochemical Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 175111113
- Full Text :
- https://doi.org/10.1016/j.tibs.2023.10.002