Surveillance for rubella virus in samples obtained from non‐immunodeficient individuals.

This article, published in the journal Pediatric Allergy & Immunology, discusses the presence of rubella virus (RuV) in individuals without immunodeficiencies. The study found that patients with cutaneous granulomas, a type of skin condition, have been found to contain RuV in lesions and shed recoverable virus. While most cases of RuV-associated granulomas have been found in individuals with immunodeficiencies, there have also been cases in individuals without clear host defense compromise. The study surveyed the presence of vaccine strain RuV (VDRV) in samples from non-immune-deficient individuals and found no evidence of the virus. These findings suggest that VDRV is not a common commensal and support the idea that it is a pathogen. The study also discusses the need for further research to understand the variables governing VDRV-associated inflammatory disease. [Extracted from the article]