Genetically determined iron status was associated with polymyalgia rheumatica but not with giant cell arteritis: A Mendelian randomization analysis.

This article summarizes a study published in the International Journal of Rheumatic Diseases that explores the genetic association between iron status and two rheumatic diseases: polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). The study used a method called Mendelian randomization (MR) to analyze genetic variants related to iron status and their connection to PMR and GCA. The findings indicate that genetically determined iron status is linked to a decreased risk of PMR but not GCA. The study suggests that iron supplementation may be a potential strategy for preventing or treating PMR, but further research is needed to confirm these findings. [Extracted from the article]