Synthesis of in-situ magnetized MOF-cellulose membranes for high-efficiency enrichment of diamide insecticides in vegetables and determination by LC-MS/MS.

This study presents a novel, eco-friendly composite adsorbent material designed for the magnetic solid-phase extraction of diamide insecticides from vegetable samples. The membrane, denoted as Fe-MMm, was incorporated with a cellulose framework embedded with Metal-Organic Frameworks (MOFs) and Multi-Walled Carbon Nanotubes (MWCNTs) magnetized with Fe 3 O 4. This innovative material streamlined the conventional solid-phase extraction process, simplifying the sample pre-treatment. By combining it with liquid chromatography tandem mass spectrometry (LC-MS/MS), the method achieves significantly enhanced extraction efficiency through systematic optimization of experimental parameters, including adsorbent selection, pH, ionic strength, adsorption time, and elution time. The method had a wide linear range of 0.1–1000 ng/mL and an exceptionally low detection limit ranging from 0.023 to 0.035 ng/mL. The successful identification of diamide insecticides in vegetable samples underscores the potential of Fe-MMm as a robust material for sample pretreatment in analytical applications. [Display omitted] • The MOF and MWCNTs@Fe 3 O 4 are embedded in the skeleton of MFC. • A solid-phase extraction method based on Fe-MMms was proposed and detected using LC-MS/MS. • Fe-MMm demonstrates excellent reusability in solid-phase extraction, with minimal performance changes after 10 uses. • The method exhibits extremely high sensitivity and a wide linear range, with an exceptionally low detection limit ranging from 0.023 to 0.035 ng/mL. [ABSTRACT FROM AUTHOR]