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A Rare Case of Disseminated Histoplasmosis Presenting with Hemophagocytic Lymphohistiocytosis.

Authors :
Agarwal, Kriti
Yadav, Meghna
Tewari, Vanmalini
Source :
Medical Journal of Dr. D.Y. Patil Vidyapeeth. Nov/Dec2023, Vol. 16 Issue 6, p984-988. 5p.
Publication Year :
2023

Abstract

Hemophagocytic lymphohistiocytosis (HLH) encompasses a wide spectrum of causes, characterized by excessive immune system activation and release of a cascade of inflammatory markers. HLH can be familial or primary and secondary, secondary being more common. Secondary HLH holds primary concern as it involves treatable causes and hence timely diagnosis and appropriate treatment are of utmost importance in patient care. Our case report is of a 34‑year‑old immunocompetent male with a history of fever of 5 days duration along with breathlessness, myalgia, and cough at the onset, but the symptoms kept deteriorating over a period of 1.5 months. Due to the wide range of clinical presentations and overlap of symptoms, an array of differentials was considered, however prioritizing an infectious cause led to our final diagnosis in this case. The patient succumbed to the disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
25898302
Volume :
16
Issue :
6
Database :
Academic Search Index
Journal :
Medical Journal of Dr. D.Y. Patil Vidyapeeth
Publication Type :
Academic Journal
Accession number :
174898397
Full Text :
https://doi.org/10.4103/mjdrdypu.mjdrdypu_502_21