HRR, PLR 与中重度颅脑损伤患者短期死亡的关系研究.

Objective: To explore the relationship between hemoglobin to red blood cell distribution width ratio (HRR), platelet to lymphocyte ratio (PLR), and short-term mortality of patients with moderate to severe traumatic brain injury (TBI) . Methods: The medical records of 162 patients with moderate to severe TBI who were admitted to Xuzhou Medical University Affiliated Hospital from September 2019 to September 2021 were retrospectively collected, and the patients were divided into death group and survival group based on their survival status within 30d of admission. The HRR and PLR were calculated, the influencing factors of short-term mortality of patients with moderate to severe TBI was analysed by multivariate Logistic regression, and the predictive value of the Glasgow Coma Scale (GCS) scores combined with HRR and PLR for short-term mortality of patients with moderate to severe TBI was analysed by the receiver operating characteristic (ROC) curve. Results: The mortality rate of 162 patients with moderate to severe TBI within 30 d of admission was 35.80% (58/162) . Compared with the survival group, the HRR decreased and PLR increased of the death group (P＜0.05) .The multivariate Logistic regression analysis showed that GCS scores less than 9 scores, dilated pupils, brain hernia, HRR decreased and PLR increased were independent risk factors for short-term mortality of patients with moderate to severe TBI (P＜0.05) . The ROC curve analysis showed that the area under the curve for predicted short-term mortality of patients with moderate to severe TBI by HRR and PLR combined with GCS scores was the largest, which was 0.924. Conclusion: HRR decrease and PLR increase are associated with short-term mortality of patients with moderate to severe TBI, which may become an auxiliary predictor of short-term mortality of patients with moderate to severe TBI, combining with HRR and PLR on the basis of GCS scores can enhance the predictive value of short-term mortality of patients with moderate to severe TBI. [ABSTRACT FROM AUTHOR]