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Development and validation of a scoring system to predict esophagogastroduodenoscopy necessity.

Authors :
Yang, Jing
Yan, Jing Shuang
Xiong, Cen Xi
Zhang, Xiao Mei
Shen, Lei
Zhi, Jun Li
Ma, Shu Yun
Dong, Hong Xia
Yang, Yun Sheng
Source :
Journal of Digestive Diseases. Dec2023, Vol. 24 Issue 12, p671-680. 10p.
Publication Year :
2023

Abstract

Objective: This study aimed to develop and validate a scoring system for predicting the need for esophagogastroduodenoscopy (EGD) in clinical practice to enhance accuracy and reduce misapplications. Methods: From February 2021 to April 2022, outpatients scheduled for EGD at the Department of Gastroenterology in our hospital were recruited. Patients completed the system evaluation by providing clinical symptoms, relevant medical history, and endoscopic findings. Patients were randomly divided into the training and validation cohorts (at 2:1 ratio). The optimal algorithm was selected from five alternatives including a parallel test. Six physicians participated in a human‐computer comparative validation. Sensitivity and negative likelihood ratio (−LR) were used as the primary indicators. Results: Altogether 865 patients were enrolled, with 578 in the training cohort and 287 in the validation cohort. The scoring system comprised 21 variables, including age, 13 typical clinical symptoms, and seven medical history variables. The parallel test was selected as the final algorithm. Positive EGD findings were reported in 54.5% of the training cohort and 62.7% of the validation cohort. The scoring system demonstrated a sensitivity of 79.0% in the training cohort and 83.9% in the validation cohort, with −LR being 0.627 and 0.615, respectively. Compared to physicians, the scoring system exhibited higher sensitivity (84.0% vs 68.7%, P = 0.02) and a lower −LR (1.11 vs 2.41, P = 0.439). Conclusions: We developed a scoring system to predict the necessity of EGD using a parallel test algorithm, which was user‐friendly and effective, as evidenced by single‐center validation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17512972
Volume :
24
Issue :
12
Database :
Academic Search Index
Journal :
Journal of Digestive Diseases
Publication Type :
Academic Journal
Accession number :
174881438
Full Text :
https://doi.org/10.1111/1751-2980.13241