Iron doped nickel oxide nanoparticle modified carbon paste electrode sensor for paracetamol in presence of ascorbic acid: A voltammetric study.

This manuscript reveals the synthesis of ferric doped nickel oxide (Fe–NiO) nanoparticle via a co-precipitation method and is depicted by XRD, SEM and EDS analysis. It is utilized as modifier at bare CPE with analysis of ascorbic acid (AA). AA (vitamin-C) found in citrus fruits and vegetables, it is acts as essential nutrients involved in tissue repair, making of collagen and enzymatic constructions of certain neuro transmitters. The Fe–NiO/MCPE brings the excellent selectivity and sensitivity towards AA in existence of Paracetamol (PA) by using cyclic voltammetry and differential pulse voltammetry. The experimental parameters like pH, sweep rate and concentration studied at 0.2 M PBS solution for the investigation of AA and PA. The Fe–NiO/MCPE is used for the illustration of AA and PA, The limit of detection for both AA and PA is 4.47 μM and 1.84 μM respectively. The prepared sensor can be used for the resolve of AA in real sample investigation. [Display omitted] • The synthesis of undoped Nickel Oxide and Iron doped Nickel Oxide nanoparticle via co-precipitation method. • Novel Fe–NiO/modified carbon paste electrode based sensor was fabricated. • Excellent electrocatalytic activity towards PA and AA was accomplished. • The practical feasibility of the developed sensor was performed very well. • An excellent analytical performance of designed sensor towards detection of AA and PA in real sample analysis. [ABSTRACT FROM AUTHOR]