Re: exposure to phenoxyacetic acids and glyphosate as risk factors for non-Hodgkin lymphoma.

The letter to the editor responds to a recent paper by Hardell and colleagues that investigated the risks of non-Hodgkin lymphoma (NHL) and hairy cell leukemia following exposure to glyphosate and phenoxyacetic acid herbicides. The authors of the letter argue that the methodological approaches used by Hardell et al. introduced bias and limitations that impacted the validity of their findings. They highlight concerns about recall bias, the construction of the reference group, small sample sizes, regression methods, and participation rates. The authors disagree with Hardell et al.'s conclusions and suggest that cohort studies provide more reliable evidence on the risks of glyphosate exposure and NHL. [Extracted from the article]