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A - 91 Serial Neuropsychological Evaluations of a Woman with Neuropsychiatric Systemic Lupus Erythematosus and Immunotherapy Treatment.

Authors :
Greenfield, Naomi
McGinley, John
Weiss, Erica F
Bronshteyn, Diana
Facchini, Ronda
Stimmel, Marnina B
Source :
Archives of Clinical Neuropsychology. Oct2023, Vol. 38 Issue 7, p1257-1257. 1p.
Publication Year :
2023

Abstract

Objective: Neuropsychiatric System Lupus Erythematosus (NP-SLE) is a subtype of SLE characterized by chronic or episodic neurologic and/or psychiatric central nervous system features. The neuropsychological profile of NP-SLE is not well-established. Here we present serial evaluations of a woman with confirmed NP-SLE who underwent subsequent medical intervention. This case study adds to the growing body of literature demonstrating the role neuropsychology plays in the care of patients with NP-SLE. Method: This was an evaluation of a 25-year-old woman with NP-SLE. Initial testing took place inpatient prior to treatment with immunotherapy treatment subsequent evaluations were outpatient at 1 month, 4 months and 8 months post-treatment. Results: Inpatient evaluation revealed a woman of at least average premorbid abilities with suboptimal performances across cognitive domains including reduced speed of processing and notable difficulty with planning and organization. Evaluation 1 month later evidenced worsening cognitive and motoric performances across tasks which led to adjustment of medical management. Evaluation at 4 months demonstrated a positive trend and some improved cognitive functioning; 8-month evaluation confirmed improvement in global cognition and functioning with suspected return to premorbid abilities. Conclusions: This case provides an example of NP-SLE neuropsychological profile over time and demonstrates the beneficial impact of correct diagnosis and medical regimen. It also highlights the role of serial neuropsychological assessment in the management of complex neurological disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
08876177
Volume :
38
Issue :
7
Database :
Academic Search Index
Journal :
Archives of Clinical Neuropsychology
Publication Type :
Academic Journal
Accession number :
174274886
Full Text :
https://doi.org/10.1093/arclin/acad067.108