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Prevalence and correlates of DSM-5 opioid withdrawal syndrome in U.S. adults with non-medical use of prescription opioids: results from a national sample.
- Source :
-
American Journal of Drug & Alcohol Abuse . 2023, Vol. 49 Issue 6, p799-808. 10p. - Publication Year :
- 2023
-
Abstract
- Background: In the U.S. non-medical use of prescription opioids (NMOU) is prevalent and often accompanied by opioid withdrawal syndrome (OWS). OWS has not been studied using nationally representative data. Objectives: We examined the prevalence and clinical correlates of OWS among U.S. adults with NMOU. Methods: We used data from 36,309 U.S. adult participants in the 2012–2013 National Epidemiologic Survey on Alcohol and Related Conditions-III, 1,527 of whom reported past 12-month NMOU. Adjusted linear and logistic regression models examined associations between OWS and its clinical correlates, including psychiatric disorders, opioid use disorder (OUD; excluding the withdrawal criterion), medical conditions, and healthcare utilization among people with regular (i.e. ≥3 days/week) NMOU (n = 534). Results: Over half (50.4%) of the sample was male. Approximately 9% of people with NMOU met criteria for DSM-5 OWS, with greater prevalence of OWS (∼20%) among people with regular NMOU. Individuals with bipolar disorder, dysthymia, panic disorder, and borderline personality disorder had greater odds of OWS (aOR range = 2.71–4.63). People with OWS had lower mental health-related quality of life (β=-8.32, p <.001). Individuals with OUD also had greater odds of OWS (aOR range = 26.02–27.77), an association that increased with more severe OUD. People using substance use-related healthcare services also had greater odds of OWS (aOR range = 6.93–7.69). Conclusion: OWS was prevalent among people with OUD and some psychiatric disorders. These findings support screening for OWS in people with NMOU and suggest that providing medication- assisted treatments and behavioral interventions could help to reduce the burden of withdrawal in this patient population. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00952990
- Volume :
- 49
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- American Journal of Drug & Alcohol Abuse
- Publication Type :
- Academic Journal
- Accession number :
- 174160715
- Full Text :
- https://doi.org/10.1080/00952990.2023.2248646