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Role of the Insulin-like Growth Factor (IGF) Axis in Diseases.

Authors :
Perks, Claire M.
Source :
International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16969. 3p.
Publication Year :
2023

Abstract

The text discusses the role of the insulin-like growth factor (IGF) axis in various diseases. The IGF axis is a complex system that includes ligands, receptors, binding proteins, and proteases. It plays a crucial role in growth, development, metabolism, and cell survival. Dysregulation of the IGF axis has been linked to diseases such as Alzheimer's disease and cancer. The text highlights the importance of understanding the IGF axis and its activity in order to develop effective treatments. Several studies are mentioned that explore the role of the IGF axis in cancer, autoimmune diseases, and fibrosis. The text emphasizes the need for further research to effectively target the IGF axis. [Extracted from the article]

Details

Language :
English
ISSN :
16616596
Volume :
24
Issue :
23
Database :
Academic Search Index
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
174116496
Full Text :
https://doi.org/10.3390/ijms242316969